CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) emerges as a tool for agriculture. Applied to plant breeding, this technology has the potential to increase productivity cost-effectively within a short timeframe. The objective of this study was to assess the biotechnological potential of CRISPR-based solutions in agriculture through a systematic review. The search was performed on February 2021 using the keyword "plant breeding AND CRISPR" in the title, abstract, and/or keywords of scientific publications - and analyzed using the statistical package Bibliometrix in R software - and the front page of patent files. A total of 348 scientific articles were retrieved from the Scopus and Web of Science databases. And 63 patented innovations were retrieved from the WIPO (World Intellectual Property Organization) database. The number of articles and patents has increased exponentially throughout the years. China has the lead in R&D (research and development) in the field, followed by the United States, Japan, Germany, France, and Canada. CRISPR has been mostly employed in studies of genome editing of crops such as maize, potato, tomato, rice and, soybean and innovations for rice, tomato, alfalfa, and mung bean. Patent registers were mostly related to code C12N and A01H of the International Patent Code. Genome editing via CRISPR has been established as a highly relevant tool for biotechnology. The research and development of CRISPR-based solutions in agriculture are on an ascending curve. This study represents the current scenario and may be expanded in the future to support policymakers and R&D investments.